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Fig. 6 | Clinical Epigenetics

Fig. 6

From: Epigenomic profiling of isolated blood cell types reveals highly specific B cell smoking signatures and links to disease risk

Fig. 6

Examples of mechanistic linkage of epigenome-wide association study (EWAS) smCpG with disease risk. A SmCpG (cg03707168, red bar) in PPP1R15A exon 2 associated with COVID-19 infection and reticulocyte count via single nucleotide polymorphism (SNP) rs4801778, and other traits via rs595982 and rs4347731. B The B cell-specific smCpG in NFKBIA gene (cg04545963, red bar) linked via mQTL and eQTL SNPs (positions displayed by black bars) to GWAS of lung function, asthma, and several other disease risk and traits

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Clinical Epigenetics

ISSN: 1868-7083

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