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Table 2 Description of the ART/hypofertile in vivo and in vitro subgroups

From: Capturing sex-specific and hypofertility-linked effects of assisted reproductive technologies on the cord blood DNA methylome

 

In vivo group

n = 17

In vitro group

n = 20

p Value

ART technique (ICSI/IVFa)

16/4

Number with blastocyst transfers

20

Aetiology for hypofertility

 Male

2

9

0.27

 Female

3

3

 Male + female

2

1

 Unexplained

2

7

Obstetrical issues (M/Fb)

 Normal

13 (8/5)

12 (6/6)

0.58

 Prematurity alone

1 (0/1)

1 (0/1)

 Gestational diabetes (GD) alone

2 (2/0)

2 (2/0)

 Pre-eclampsia alone

1 (0/1)

1 (0/1)

 Pre-eclampsia + prematurity

0

3 (1/2)

 Pre-eclampsia + GD

0

1 (0/1)

Spontaneous conception after > 1 year of unprotected intercourse

8

Infant sex (M/Fb)

10/7

9/11

0.51

  1. aICSI, intracytoplasmic sperm injection; IVF, in vitro fertilization
  2. bM, male; F, female
  3. For all variables, N is shown and fisher’s exact test or chi-square test was performed to compare groups