Skip to main content
Fig. 3 | Clinical Epigenetics

Fig. 3

From: Capturing sex-specific and hypofertility-linked effects of assisted reproductive technologies on the cord blood DNA methylome

Fig. 3

ART/hypofertility affects DNA methylation in regions of biological importance. Number of hypo- and hypermethylated differentially methylated regions (DMRs) between ART and control groups for A males and B females. Number of DMCs merged within each hypo- and hypermethylated DMR for C males and D females. The average number of DMCs/region is indicated by a red square. Genes annotated to DMRs containing the highest number of DMCs are identified. All significant biological processes from Gene Ontology analysis on all DMRs located within genic regions for the ART versus Control analysis in E males and F females. The number of observed genes associated with each term is indicated within bars. Enrichment is defined as the proportion of observed genes compared to the number annotated within the whole dataset and is indicated by bar colour. The dotted line represents the significance threshold: weighted Fisher’s p value < 0.01

Back to article page

Clinical Epigenetics

ISSN: 1868-7083

Contact us