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Table 1 Descriptive statistics of the study sample

From: Time to relapse in chronic lymphocytic leukemia and DNA-methylation-based biological age

 

Early relapse

Late relapse

p

N, n (%)

17 (48.6)

18 (51.4)

–

Female, n (%)

6 (35.3)

4 (22.2)

0.458

Age at diagnosis, mean (SD), years

55.4 (10.1)

55.8 (8.9)

0.882

Time to first treatment, mean (SD), years

2.1 (3.3)

2.0 (1.3)

0.875

Time to relapse, mean (SD), years

1.5 (0.5)

5.2 (2.1)

< 0.001

IEAA, mean (SD), years

− 1.6 (17.6)

1.5 (13.8)

0.573

EEAA, mean (SD), years

6.8 (17.8)

− 6.4 (18.0)

0.036

PhenoAA, mean (SD), years

2.3 (16.7)

− 2.2 (22.1)

0.507

GrimAA, mean (SD), years

− 3.2 (6.0)

3.1 (5.2)

0.002

  1. IEAA, intrinsic epigenetic age acceleration; EEAA, extrinsic epigenetic age acceleration; PhenoAA, PhenoAge acceleration; GrimAA, GrimAge acceleration