Table 5 Summary of CD8+, CD4+ and FOXp3+ T cell in pre- and post-treatment biopsies, as recorded in tumor, and in the stroma
Group | Variable CI t | n complete both | Mean difference | p value t test |
|---|---|---|---|---|
Overall | ||||
Tumor log(CD8) [− 0.63, 0.12] | tumor.CD8 | 13 | − 0.256 | 0.16 |
Tumor log(CD8/CD4) [− 0.37, 0.48] | tumor.CD8.CD4 | 13 | 0.054 | 0.79 |
Tumor Foxp3 [− 0.81, 0.07] | tumor.Foxp3 | 13 | − 0.371 | 0.09 |
Stroma Foxp3 [− 0.79, 0.34] | stroma.Foxp3 | 13 | − 0.225 | 0.40 |
Aza | ||||
Tumor log(CD8) [− 1.28, 1.02] | tumor.CD8 | 4 | − 0.13 | 0.74 |
Tumor log(CD8/CD4) [− 0.68, 0.91] | tumor.CD8.CD4 | 4 | 0.112 | 0.68 |
Tumor Foxp3 [− 1.96, 1.88] | tumor.Foxp3 | 4 | − 0.04 | 0.95 |
Stroma Foxp3 [− 1.91, 2.03] | stroma.Foxp3 | 4 | 0.058 | 0.93 |
Rom | ||||
Tumor log(CD8) [− 1.35, 0.16] | tumor.CD8 | 5 | − 0.596 | 0.09 |
Tumor log(CD8/CD4) [− 1.47, 1.11] | tumor.CD8.CD4 | 5 | − 0.181 | 0.72 |
Tumor Foxp3 [− 1.21, 0.19] | tumor.Foxp3 | 5 | − 0.513 | 0.11 |
Stroma Foxp3 [− 1.84, 0.84] | stroma.Foxp3 | 5 | − 0.501 | 0.36 |
Aza + Rom | ||||
Tumor log(CD8) [− 0.62, 0.70] | tumor.CD8 | 4 | 0.043 | 0.85 |
Tumor log(CD8/CD4) [− 0.30, 0.88] | tumor.CD8.CD4 | 4 | 0.289 | 0.22 |
Tumor Foxp3 [− 0.88, − 0.18] | tumor.Foxp3 | 4 | − 0.525 | 0.02 |
Stroma Foxp3 [− 0.78, 0.45] | stroma.Foxp3 | 4 | − 0.164 | 0.46 |