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Table 2 Unstandardized coefficients from regression models for the direct association between the ADHD Polygenic Score (ADHD-PGS) and epigenetic aging, as indexed by the DNA methylation-based indicator of GrimAge

From: ADHD genetic burden associates with older epigenetic age: mediating roles of education, behavioral and sociodemographic factors among older adults

Parameter

Beta coefficient

SE

p-value

Intercept

74.79

0.30

< .0001

Age

0.76

0.01

< .0001

Gender: male

3.43

0.18

< .0001

ADHD-PGS

0.49

0.09

< .0001

Model R2

  

74.85%

  1. Models are adjusted for ancestral principal components as covariates for population substructure
  2. SE = standard error, R2 = Variance explained by the model
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Clinical Epigenetics

ISSN: 1868-7083

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