Impact of intrauterine exposure to maternal diabetes on preterm birth: fetal DNA methylation alteration is an important mediator

Table 3 Differentially methylated regions (DMRs) identified by DMRcate in 500 bp window

DMR coordinates	Chr	CpGs comprising the DMR	Width	No. of CpG	Overlapping genes	Fisher	HMFDR
19631464–19631485	17	cg04384031; cg04492567	22	2		0.004	0.022
32908466–32908718	6	cg00575744; cg10310595; cg12840248; cg16236263; cg22324029	253	5	HLA-DMB	0.030	0.089
57915665–57915740	17	cg12054453; cg01409343; cg16936953	76	3	VMP1	0.103	0.151
32120863– 32120955	6	cg13934406; cg06025456; cg23359665; cg02956248; cg17113856; cg16481280; cg06108383	93	7	PRRT1	0.923	0.588

Chr Chromosome, Fisher Fisher's multiple comparison statistic, HMFDR Harmonic mean of the individual component FDRs

ISSN: 1868-7083