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Table 1 All DMCs and DMRs that are significantly different between control F0 or control F1 and various SSCT groups and subgroups (n = 3 in the F0, n = 5 per offspring subgroup in the F1 and F2)

From: Sperm DNA methylation is predominantly stable in mice offspring born after transplantation of long-term cultured spermatogonial stem cells

 

All measured DMCs

Number of CpGs displaying > 25% difference

Percentage of > 25% over of all measured CpGs

SSCT F0

82,296

2984

3.63%

SSCT F1

714,806

2892

0.40%

SSCT F2

504,893

833

0.16%

SSCT F2/M

609,442

2695

0.44%

SSCT F2/P

664,355

2823

0.42%

 

All measured DMRs

Number of DMRs displaying > 25% difference

Percentage > 25% difference of all measured DMRs

SSCT F0

19,621

1105

5.63%

SSCT F1

138,480

500

0.36%

SSCT F2

113,616

153

0.13%

SSCT F2/M

128,075

477

0.37%

SSCT F2/P

133,762

491

0.37%

  1. F2/M—F2 generated from the maternal line, F2/P—F2 generated from the paternal line