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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Sperm DNA methylation is predominantly stable in mice offspring born after transplantation of long-term cultured spermatogonial stem cells

Fig. 4

Validation of RRBS results with BSP of Tal2 from individual sperm samples. Overall CpGs presented the following averages per group: control F1 24.7% ± 4.4%, SSCT F1 17.4% ± 4.5%, SSCT F2/M 22.7% ± 9.3%, SSCT F2/P 14.5% ± 3.2% presenting the highest difference of 10% methylation difference between SSCT and control (n = 5 per offspring subgroup in the F1 and F2). F2/M—F2 generated from the maternal line, F2/P—F2 generated from the paternal line

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Clinical Epigenetics

ISSN: 1868-7083

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