Fig. 1
From: Distinguishable DNA methylation defines a cardiac-specific epigenetic clock
Mongelli&Panunzi (M&P) blood model. Red dots: blood samples (n = 313); blue dots: cardiac tissue samples (n = 313). A The correlation of chronological age and DNAmAge. Red dots align with the bisector, while blue dots do not. Chronological age of the sample (mean ± SD) 66.5 ± 9.7 years; M&P blood-specific formula on blood samples age: 65.7 ± 7.6 years (paired T test of chronological age vs. blood DNAmAge p = ns); M&P blood-specific on cardiac tissue samples: 24.0 ± 10.0 years (paired t test chronological age vs. cardiac tissue DNAmAge p value < 0.0001). B DeltaAges of blood and cardiac tissue. Blood – 0.40 ± 5.30 years; cardiac tissue − 42.0 ± 11.30. paired T test: p < 0.0001