Table 2 The results of epigenome-wide association study on diastolic blood pressure (p < 1 × 10–4)
Chromosome | Position (bp) | Coefficient | p-value | FDR | Ensembl gene ID | HGNC symbol |
|---|---|---|---|---|---|---|
chr1 | 228,195,277 | 0.028 | 5.764E-08 | 0.010 | ENSG00000154342 | WNT3A |
chr1 | 228,195,289 | 0.029 | 1.291E-07 | 0.010 | ENSG00000154342 | WNT3A |
chr1 | 2,391,479 |  − 0.020 | 1.540E-07 | 0.010 | ENSG00000149527 | PLCH2 |
chr1 | 228,195,292 | 0.029 | 1.633E-07 | 0.010 | ENSG00000154342 | WNT3A |
chr1 | 228,195,260 | 0.029 | 2.857E-07 | 0.014 | ENSG00000154342 | WNT3A |
chr6 | 100,909,431 | 0.026 | 2.450E-06 | 0.090 | ENSG00000112246 | SIM1 |
chr1 | 2,391,466 |  − 0.018 | 2.541E-06 | 0.090 | ENSG00000149527 | PLCH2 |
chr12 | 74,797,036 |  − 0.047 | 4.032E-06 | 0.125 | ENSG00000253719 | ATXN7L3B |
chr6 | 100,909,425 | 0.025 | 5.889E-06 | 0.163 | ENSG00000112246 | SIM1 |
chr12 | 74,797,017 |  − 0.044 | 7.783E-06 | 0.185 | ENSG00000253719 | ATXN7L3B |
chr7 | 25,898,451 | 0.020 | 8.166E-06 | 0.185 | ENSG00000223561 | LOC646588 |
chr12 | 74,797,049 |  − 0.037 | 9.188E-06 | 0.191 | ENSG00000253719 | ATXN7L3B |
chr7 | 25,898,447 | 0.020 | 1.231E-05 | 0.236 | ENSG00000223561 | LOC646588 |
chr17 | 38,088,968 | 0.185 | 1.593E-05 | 0.257 | ENSG00000264968 | NA |
chr6 | 66,373,850 | 0.055 | 1.624E-05 | 0.257 | ENSG00000188107 | EYS |
chr12 | 74,797,053 |  − 0.035 | 1.720E-05 | 0.257 | ENSG00000253719 | ATXN7L3B |
chr9 | 80,272,835 |  − 0.068 | 1.752E-05 | 0.257 | ENSG00000156049 | GNA14 |
chr1 | 228,195,243 | 0.029 | 1.988E-05 | 0.273 | ENSG00000154342 | WNT3A |
chr9 | 80,272,842 |  − 0.066 | 2.086E-05 | 0.273 | ENSG00000156049 | GNA14 |
chr9 | 80,272,845 |  − 0.066 | 2.338E-05 | 0.288 | ENSG00000156049 | GNA14 |
chr6 | 66,373,857 | 0.053 | 2.469E-05 | 0.288 | ENSG00000188107 | EYS |
chr9 | 80,272,847 |  − 0.065 | 2.663E-05 | 0.288 | ENSG00000156049 | GNA14 |
chr12 | 74,797,056 |  − 0.034 | 2.825E-05 | 0.293 | ENSG00000253719 | ATXN7L3B |
chr9 | 138,637,356 |  − 0.013 | 4.158E-05 | 0.400 | ENSG00000107147 | KCNT1 |
chr19 | 35,324,068 | 0.168 | 4.340E-05 | 0.400 | ENSG00000267767 | LINC01801 |
chr19 | 47,635,288 |  − 0.021 | 4.779E-05 | 0.425 | ENSG00000142230 | SAE1 |
chr9 | 138,637,337 |  − 0.011 | 5.604E-05 | 0.462 | ENSG00000107147 | KCNT1 |
chr12 | 74,796,990 |  − 0.040 | 5.764E-05 | 0.462 | ENSG00000253719 | ATXN7L3B |
chr17 | 38,088,944 | 0.171 | 5.910E-05 | 0.462 | ENSG00000264968 | NA |
chr9 | 124,308,134 | 0.014 | 6.588E-05 | 0.462 | ENSG00000136848 | DAB2IP |
chr9 | 124,308,131 | 0.014 | 6.979E-05 | 0.462 | ENSG00000136848 | DAB2IP |
chr19 | 47,635,313 |  − 0.017 | 7.074E-05 | 0.462 | ENSG00000142230 | SAE1 |
chr5 | 30,864,593 | 0.145 | 7.349E-05 | 0.462 | ENSG00000241668 | RPL19P11 |
chr9 | 124,308,128 | 0.014 | 7.539E-05 | 0.462 | ENSG00000136848 | DAB2IP |
chr11 | 100,999,098 | 0.026 | 8.179E-05 | 0.462 | ENSG00000082175 | PGR |
chr16 | 8,619,841 | 0.014 | 8.388E-05 | 0.462 | ENSG00000232258 | TMEM114 |
chr9 | 124,308,155 | 0.013 | 8.503E-05 | 0.462 | ENSG00000136848 | DAB2IP |
chr10 | 103,551,798 | 0.150 | 8.742E-05 | 0.462 | ENSG00000198408 | OGA |
chr17 | 38,088,933 | 0.169 | 8.800E-05 | 0.462 | ENSG00000264968 | NA |
chr11 | 100,999,104 | 0.025 | 8.815E-05 | 0.462 | ENSG00000082175 | PGR |
chr9 | 124,308,115 | 0.014 | 9.133E-05 | 0.462 | ENSG00000136848 | DAB2IP |
chr9 | 124,308,162 | 0.012 | 9.381E-05 | 0.462 | ENSG00000136848 | DAB2IP |
chr10 | 103,551,806 | 0.148 | 9.390E-05 | 0.462 | ENSG00000198408 | OGA |