Fig. 6

Low-dose selenite treatment synergizes with targeted therapy. A Loewe synergy scores and maps of selenite and osimertinib in H1975. The rectangles represented the most synergistic area. B % viability of single-agent 1 µM Se, 10 nM osimertinib, and their combination. C Loewe synergy scores and maps of selenite and adagrasib in H358. The rectangles represented the most synergistic areas. D % viability of single-agent 1 µM Se, 1 nM adagrasib and their combination