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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Long-term impact of paediatric critical illness on the difference between epigenetic and chronological age in relation to physical growth

Fig. 3

The 4-year time course of changes in height and weight for healthy children versus PICU-patients. Changes from baseline are presented as means and standard errors. Former PICU-patients are indicated in red and healthy control children in green. PICU-patients grew less in height, but transiently gained weight, as compared with matched healthy children over the 4-year time course (panels A and B). Growth in height was more stunted in PICU-patients ≥ 6 years of age at time of exposure to critical illness as compared with those aged < 6 years (panels C and E). Also, the transient weight gain in former PICU-patients was more present in those aged ≥ 6 years at time of exposure as compared with those aged < 6 years (panels D and F). ∆: delta, 2y FU: 2-year follow-up, 4y FU: 4-year follow-up, N: number, PICU: paediatric intensive care unit

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