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Fig. 3 | Clinical Epigenetics

Fig. 3

From: HTRA1 methylation in peripheral blood as a potential marker for the preclinical detection of stroke: a case–control study and a prospective nested case–control study

Fig. 3

Methylation level of HTRA1 in the peripheral blood DNA as a marker for the early detection of stroke. ROC curve analyses for the discriminatory power of HTRA1 methylation to distinguish stroke cases with onset time A < 2 years, B ≤ 1.5 years, C ≤ 1.32 years, and D ≤ 1 year from controls. The ROC analyses were performed by logistic regression using all the analyzed CpG sites and stroke-related variables including age, sex, smoking, drinking, hypertension, diabetes, TC, TG, HDL-C and LDL-C

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