Fig. 7

Relationships between SUV39H1 and DNA methylation, DNMT3a, and H3K4me3 at the CREMα promoter. a Relative DNA methylation level at the CREMα promoter in normal and SLE CD4⁺ T cells were examined by MeDIP combined with qPCR. b The correlation between SUV39H1 enrichment and DNA methylation level at the CREMα promoter in SLE CD4⁺ T cells. c Relative DNMT3a enrichment at the CREMα promoter in normal and SLE CD4⁺ T cells were examined by ChIP combined with qPCR. d The correlation between SUV39H1 enrichment and DNMT3a enrichment at the CREMα promoter in SLE CD4⁺ T cells. e Relative H3K4me3 enrichment at the CREMα promoter in normal and SLE CD4⁺ T cells were examined by ChIP combined with qPCR. f The correlation between SUV39H1 enrichment and H3K4me3 enrichment at the CREMα promoter in SLE CD4⁺ T cells. All reactions were performed in triplicate