Fig. 2

Bindings of SUV39H1 and SUV39H2 at the CREMα promoter in CD4⁺ T cells. a, b Relative SUV39H1 (a) and SUV39H2 (b) bindings at the CREMα promoter in normal and SLE CD4⁺ T cells were assessed by ChIP combined with qPCR. Input DNA was used as endogenous control, and IgG was used as negative control. c The correlation between SUV39H1 binding and H3K9me3 level at the CREMα promoter in SLE CD4⁺ T cells. d The correlation between SUV39H1 binding at the CREMα promoter and CREMα mRNA expression in SLE CD4⁺ T cells. e The correlation between SUV39H1 binding at the CREMα promoter in SLE CD4⁺ T cells and SLEDAI. All reactions were run three times