Association of nutritional glycaemic indices with global DNA methylation patterns: results from the Moli-sani cohort

Table 2 Association of dietary glycaemic parameters with methylation (5mC) and hydroxymethylation (5hmC) measures

Glycaemic parameter	Epigenetic marker	Beta	SE	T-stat	P value
Glycaemic load	5mC	− 0.146	0.060	− 2.441	0.015
Glycaemic index	5mC	− 0.073	0.027	− 2.699	0.007
Glycaemic load	5hmC	− 0.028	0.068	− 0.412	0.680
Glycaemic index	5hmC	− 0.084	0.030	− 2.77	0.006

These associations were adjusted for age, sex and educational attainment, white blood cell fractions, smoking, leisure time physical activity, abdominal obesity, alcohol intake, prevalent diabetes, hyperlipidaemia and cancer

ISSN: 1868-7083