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Table 1 Major eukaryotic acetyltransferases

From: NAA60 (HAT4): the newly discovered bi-functional Golgi member of the acetyltransferase family

 

Family

Name

Alternative name

Cell localization

Amino acid target

HAT

GNAT

HAT1

KAT1

Nucleus

K

NAA60

NatF/HAT4/NAT15

Golgi

K

KAT2A

GCN5

Cytosol

K

KAT2B

PCAF

Nucleus

K

NAT

NatA

*

Cytosol

A/S/T/G/V/C

NatB

*

Cytosol

MD/ME/MN/MQ

NatC

*

Cytosol

ML/MI/MF/MY/MK

NatD

*

Cytosol

SGRGK

NatE

*

Cytosol

M-S/T/A/V/L/I/F/Y/K

NatF

NAA60/NAT15/HAT4

Golgi

M–K/M-A/M-V/M-MS

NatG

NAA70

Chloroplast

M/A/S/T

NatH

NAA80

Cytosol

DDD/EEE

HAT

MYST

KAT5

Tip60

Nucleus

K

KAT6A

MOZ/MYST3

Nucleus

K

KAT6B

MORF/MYST4

Nucleus

K

KAT7

HBO1/MYST2

Nucleus

K

KAT8

MOF/MYST1

Nucleus

K

HAT

p300/CBP

KAT3A

CBP

Nucleus

K

KAT3B

p300

Nucleus

K

  1. HAT and NAT families’ members are grouped. The alternative names, the cell localization and the acetylated peptide target are reported