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Fig. 5 | Clinical Epigenetics

Fig. 5

From: Bariatric surgery-induced weight loss and associated genome-wide DNA-methylation alterations in obese individuals

Fig. 5

Epigenetic age acceleration (EAA) analysis using the Hannum et.al. method. It is determined by taking the residual from the regression of epigenetic age (based on β values of 71 CpG probes) on chronological age. Positive EAA values thus suggest that the epigenetic age is greater than expected based on chronological age. A EAA at different time points through the course of weight loss. B Regression estimates (beta estimate) were analyzed considering the time point 0 (pre-surgery) as reference

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