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Fig. 5 | Clinical Epigenetics

Fig. 5

From: Transient Polycomb activity represses developmental genes in growing oocytes

Fig. 5

EED is required for repressing a wide range of genes in growing oocytes that are not canonically or non-canonically imprinted or X-linked genes a Venn diagram comparing Eed oocyte DEGs against putative H3K27me3 imprinted genes [35]. b Expression of putative H3K27me3-imprinted Eed oocyte DEGs in Eed-hom oocyte relative to Eed-het. Data represent the mean transcripts per million (TPM), with Eed-het mean set to 1.0. c Venn diagram comparing Eed oocyte DEGs against known or predicted classically imprinted genes [49, 50]. d Expression of known or predicted classically imprinted Eed oocyte DEGs in Eed-hom oocyte relative to Eed-het. Data represent the mean transcripts per million (TPM), with Eed-het mean set to 1.0. e graphical representation of Eed oocyte DEGs per mega base vs chromosome for autosome and the X-chromosome. f Expression of X-linked Eed oocyte DEGs in Eed-hom oocyte relative to Eed-het. Data represent the mean transcripts per million (TPM), with Eed-het mean set to 1.0

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