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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Identification of hepatocellular carcinoma subtypes based on PcG-related genes and biological relevance with cancer cells

Fig. 3

Modulation of PcG activity affected metabolic signatures of HCC cells. A The lipid fluorescence staining of HCC cells after GSK126 or PRT4165 treatment. The white arrow indicated 10 μm. Three independent assays were analyzed and average number of lipid droplet of each field was measured. ****p < 0.001. B The fatty acid oxidation effect of HCC cell after GSK126 or PRT4165 treatment. Three independent assays were performed, and data were collected at 60- and 120-min time points. Ns, not significant; *p < 0.05; ***p < 0.005; ****p < 0.001. C Cell viability of HCC cells after glucose deprivation with or without treatment of GSK126 or PRT4165 and after supplement of palmitic acid. Three independent assays were performed. Ns, not significant; *p < 0.05; ***p < 0.005; ****p < 0.001

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