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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Identification of hepatocellular carcinoma subtypes based on PcG-related genes and biological relevance with cancer cells

Fig. 2

Two epigenetic subtypes had discrepant metabolic signatures. A Gene Set Variation Analysis (GSVA) of mRNA expression profile in HCC of different epigenetic subgroups. B Fatty acid oxidation-related genes expression profile of HCC in different epigenetic subgroups. C The downregulation of H3K27me3 and H2AK119ub protein level in HCC cells after GSK126 or PRT4165 treatment. D The downregulation of three fatty acid oxidation-related genes mRNA expression in HCC cells after GSK126 or PRT4165 treatment. β-actin (ACTB) was used as internal control. Ns, not significant; *p < 0.05; **p < 0.01; ***p < 0.005; ****p < 0.001

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Clinical Epigenetics

ISSN: 1868-7083

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