The emerging role of epigenetic regulation in the progression of silicosis

Clinical Epigenetics

Table 3 The main circRNA changes involved in silicosis

circRNA	Tissue/Cell/Patients	Expression level	Target gene	References
circ-012091	L929, HPF-a	Up	PPP1R13B	[89]
circHIPK2	HPF-a	Up	sigma-1	[90]
circHIPK3	MRC-5, NIH/3T3	Up	miR-30a-3p/FOXK2	[91]
circZC3H4	RAW264.7	Up	miR-212	[92]
circHECTD1	HPF-a	Down	HECTD1	[94]
circRNA CDR1as	Mice HBE, A549, MRC-5, NIH-3T3	Up	miR-7	[95]
cirCECTD1	Mice Pulmonary tissues of silicosis patients MML1, RAW264.7	Up/Down	HECTD1	[96]
hsa_circ_0058493	Patients	Up		[97]

ISSN: 1868-7083