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Fig. 5 | Clinical Epigenetics

Fig. 5

From: The spectrum of tuberculosis described as differential DNA methylation patterns in alveolar macrophages and alveolar T cells

Fig. 5

DNAm signatures of IGRA status. Heatmap analysis revealing a distinct DNA methylation pattern of the IGRA positives versus the IGRA negatives in alveolar macrophages (A) and alveolar T cells (B). The borderline positive samples have been added to the analysis. The heatmap is plotted from the absolute β-values of the top DMCs differentiating the groups. Cluster dendrogram is calculated using the Euclidean distance method. DNAm, DNA methylation; IGRA, interferon-gamma release assay; DMC, differentially methylated CpG-site; Con, control group; Exp, TB-exposed; Pat, TB patients; B, borderline positive; F, female; M, male; ND, no data

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Clinical Epigenetics

ISSN: 1868-7083

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