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Table 7 FUT7_CpG_1-7 methylation levels in LC patients with different clinical characteristics

From: Novel blood-based FUT7 DNA methylation is associated with lung cancer: especially for lung squamous cell carcinoma

Variables (n)

FUT7_CpG_1

FUT7_CpG_2

FUT7_CpG_3

FUT7_CpG_4

FUT7_CpG_5

FUT7_CpG_6

FUT7_CpG_7

Clinical stage

 Stage I&II (172)

0.243

0.113

0.183

0.175

0.153

0.142

0.122

 Stage III&IV (236)

0.227

0.099

0.148

0.165

0.116

0.113

0.101

 P value

0.091

0.001**

 < 0.001***

0.138

 < 0.001***

 < 0.001***

 < 0.001***

Nodule length

  ≤ 3 cm (234)

0.247

0.113

0.178

0.175

0.146

0.136

0.124

  > 3 cm (153)

0.219

0.095

0.146

0.158

0.113

0.112

0.090

 P value

0.005**

 < 0.001***

 < 0.001***

0.009**

 < 0.001***

 < 0.001***

 < 0.001***

Lymph node metastasis number

 0 (189)

0.236

0.110

0.173

0.168

0.147

0.138

0.117

 1–3 (225)

0.233

0.101

0.153

0.169

0.119

0.114

0.103

 P value

0.733

0.016*

0.025*

0.991

 < 0.001***

 < 0.001***

0.024*

Distant metastasis

 Yes (136)

0.223

0.097

0.146

0.163

0.114

0.112

0.099

 No (271)

0.239

0.109

0.172

0.172

0.141

0.132

0.115

 P value

0.117

0.003**

0.008**

0.169

 < 0.001***

0.003**

0.016*

  1. P: Mann–Whitney-U test was used to continuous data
  2. *P < 0.05; **P < 0.01; ***P < 0.001