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Table 4 Comparison between LUAD and LUSC

From: Novel blood-based FUT7 DNA methylation is associated with lung cancer: especially for lung squamous cell carcinoma

Variables

LUAD (n = 291)

LUSC (n = 81)

P value

Age, year

59.01 ± 10.68

62.54 ± 7.65

0.006**

Sex

  

 < 0.001***

Male, n (%)

127 (43.64%)

75 (92.59%)

 

History of chronic lung diseases, n (%)

15 (5.16%)

13 (16.05%)

0.001***

Personal tumor history, n (%)

9 (3.16%)

4 (5.13%)

0.407

Family tumor history, n (%)

43 (15.09%)

15 (18.52%)

0.456

Smoking

68 (23.86%)

55 (67.90%)

 < 0.001***

Alcohol drinking, n (%)

47 (16.43%)

33 (41.77%)

 < 0.001***

FUT7_CpG_1

0.240 (0.180–0.310)

0.190 (0.150–0.260)

 < 0.001***

FUT7_CpG_2

0.110 (0.080–0.135)

0.090 (0.070–0.110)

0.002**

FUT7_CpG_3

0.170 (0.110–0.230)

0.110 (0.080–0.170)

 < 0.001***

FUT7_CpG_4

0.170 (0.140–0.210)

0.150 (0.120–0.190)

 < 0.001***

FUT7_CpG_5

0.130 (0.100–0.175)

0.100 (0.070–0.130)

 < 0.001***

FUT7_CpG_6

0.130 (0.080–0.175)

0.100 (0.070–0.130)

0.002**

FUT7_CpG_7

0.110 (0.070–0.160)

0.080 (0.050–0.120)

 < 0.001***

Nodule length, mm

25.657 ± 17.893

44.894 ± 22.703

 < 0.001***

Clinical stage

  

 < 0.001***

 I, n (%)

137 (48.24%)

8 (10.81%)

 

 II, n (%)

13 (4.58%)

5 (6.76%)

 

 III, n (%)

49 (17.25%)

35 (47.30%)

 

 IV, n (%)

85 (29.93%)

26 (35.14%)

 
  1. LUAD lung adenocarcinoma, LUSC lung squamous cell carcinoma
  2. P: Mann–Whitney-U test was used to continuous data and Chi-squared test was applied to categorical data
  3. *P < 0.05; **P < 0.01; ***P < 0.001