Fig. 4
From: Epigenetic silencing of JAM3 promotes esophageal cancer development by activating Wnt signaling
The effect of JAM3 on cell cycle and apoptosis. a The effect of JAM3 on cell phase in EC cells. The bar diagram represents the percentage. b The effect of JAM3 on apoptosis in EC cells. Each experiment was repeated in triplicate. *p < 0.05. **p < 0.01. ***p < 0.001. c Western blot shows the levels of JAM3, cyclinD1, cyclin E1, cyclin A2, BAX, Bcl2, caspase3 and cleaved-caspase3. Actin: internal control. Scrambled: siRNA negative control; siRNA#2: siRNA targeting JAM3