Table 2 Regression analysis with severity z-score of depression or anxiety or having a lifetime depressive disorder as dependent variables
From: Methylation of the serotonin reuptake transporter gene and non-motor symptoms in dystonia patients
Model | Variables | R2 | B | SE | p value |
|---|---|---|---|---|---|
Linear regression; z-score depression severity | |||||
1 | CpG34 | 0.04 | 0.49 | 0.25 | 0.06 |
0.06 | |||||
Linear regression; z-score anxiety severity | |||||
1 | CpG34 | 0.04 | 0.53 | 0.29 | 0.07 |
0.07 | |||||
1 | CpG38 | 0.07 | 0.04 | ||
− 0.71 | 0.34 | 0.04 | |||
2 | 0.16 | 0.00 | |||
CpG38 | − 0.55 | 0.88 | 0.01 | ||
Age | 0.03 | 0.21 | 0.00 | ||
CGI | 0.18 | 0.01 | 0.13 | ||
3 | 0.07 | 0.03 | |||
CpG38 | − 0.66 | 1.77 | 0.08 | ||
Genotype*: | |||||
LA/LA | |||||
S/S | 0.03 | 0.63 | 0.96 | ||
Other | 0.45 | 0.46 | 0.33 | ||
Model | Variables | Nagelkerke R2 | B | SE | p value |
|---|---|---|---|---|---|
Logistic regression; Lifetime presence of Depression | |||||
1 | 0.11 | 0.00 | |||
CpG38 | 0.95 | 0.34 | 0.01 | ||
2 | 0.14 | 0.01 | |||
CpG38 | 0.96 | 0.36 | 0.01 | ||
Age | − 0.02 | 0.01 | 0.21 | ||
CGI | − 0.15 | 0.15 | 0.29 | ||
3 | 0.11 | 0.04 | |||
CpG38 | 0.89 | 0.34 | 0.01 | ||
Genotype*: | |||||
LA/LA | |||||
S/S | 0.35 | 0.68 | 0.60 | ||
Other | 0.07 | 0.02 | 0.88 |