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Table 3 Multivariate model with GAA as outcome and GES as glucocorticoid exposure epigenetic exposure score

From: Gestational age acceleration is associated with epigenetic biomarkers of prenatal physiologic stress exposure

Predictors

Gestational age acceleration (GAA)

Estimates

CI

p value

(Intercept)

1.24

−4.02 to 6.49

0.640

GES

0.38

−4.56 to 5.32

0.878

GES* sex [GIRLS]

1.29

0.04 to 2.55

0.044

Sex (Girls)

1.36

0.12 to 2.60

0.032

Mother Age

−0.03

−0.06 to 0.00

0.053

Perceived stress in relation to pregnancy

0.18

−0.04 to 0.40

0.098

Mental disorder

−0.85

−1.60 to −0.11

0.026

Time in relationship with father

−0.00

−0.01 to 0.00

0.468

Familial income

0.10

−0.12 to 0.33

0.361

Mother education

−0.07

−0.30 to 0.15

0.513

Smoking during pregnancy

0.25

−0.33 to 0.83

0.389

Cephalic circumference (z-score)

0.30

−0.03 to 0.58

0.032

Weight for age (z-score)

0.07

−0.18 to 0.32

0.569

Cell composition

0.32

−0.49 to 1.13

0.433

  1. Bold values means p < 0.05
  2. Observations: 68
  3. Asterisk means moderation model
  4. R2/R2 adjusted: 0.449/0.316