Skip to main content

Table 2 Multivariate model with GAA as outcome and i-ePGS as low-grade inflammation epigenetic exposure score

From: Gestational age acceleration is associated with epigenetic biomarkers of prenatal physiologic stress exposure

Predictors

Gestational Age Acceleration (GAA)

Estimates

CI

p value

(Intercept)

3.08

0.66–5.51

0.014

i ePGS

57.07

0.26–113.87

0.049

i ePGS * sex [GIRLS]

−38.97

−107.24 to 29.29

0.257

Sex (Girls)

−1.30

−3.75 to 1.15

0.293

Mother age

−0.03

−0.07 to 0.00

0.036

Perceived stress in relation to pregnancy

0.26

0.04–0.48

0.019

Mental disorder

−0.77

−1.50 to −0.03

0.042

Time in relationship with father

−0.00

−0.01to 0.00

0.730

Familial income

0.11

−0.12 to 0.33

0.348

Mother education

−0.10

−0.33 to 0.12

0.354

Smoking during Pregnancy

0.01

−0.56 to 0.58

0.974

Cephalic circumference (z-score)

0.24

−0.02 to 0.50

0.074

Weight for Age (z-score)

0.02

−0.26 to 0.29

0.893

Cell Composition

0.10

−0.02 to 0.22

0.109

  1. Bold values means p < 0.05
  2. Observations: 68
  3. Asterisk means moderation model
  4. R2/R2 adjusted: 0.443/0.308