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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Increased copy number of imprinted genes in the chromosomal region 20q11-q13.32 is associated with resistance to antitumor agents in cancer cell lines

Fig. 1

Example scatterplots of the copy number of selected imprinted genes at 20q11-q13.32 versus log(IC50) of antitumor agents listed in Table 1. The dashed line indicates the linear regression line. The list of cancer categories is provided under Abbreviations. ρ, Spearman correlation coefficient; r, Pearson correlation coefficient. A Copy number of GNAS-AS1 (located at 20q13.32) versus response to ispinesib mesylate. B Copy number of GNAS-AS1 versus response to BX-912. C Copy number of HM13 (at 20q11.21) versus response to axitinib. D Copy number of NNAT (at 20q11.23) versus response to ispinesib mesylate

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