Skip to main content
Fig. 7 | Clinical Epigenetics

Fig. 7

From: Genome-wide screening for differentially methylated long noncoding RNAs identifies LIFR-AS1 as an epigenetically regulated lncRNA that inhibits the progression of colorectal cancer

Fig. 7

LIFR-AS1 is a tumor suppressor in CRC. A RT-qPCR analysis of the expression of LIFR-AS1 in colon cancer cells. B LIFR-AS1 expression in HT-29 and T84 cells overexpressing LIFR-AS1 or control was measured by RT-qPCR. C Cell viabilities of HT-29 and T84 cells overexpressing LIFR-AS1 or control were determined by CCK-8 assay. D Colony formation assay of HT-29 and T84 cells overexpressing LIFR-AS1 or control. E Transwell Matrigel invasion assay was performed in HT-29 and T84 cells transfected with LIFR-AS1 or control. F Representative data of tumors in nude mice derived from colon cancer cells transfected LIFR-AS1 or control. G Tumor volume of the LIFR-AS1 and negative control groups. H Tumor weight of the LIFR-AS1 and negative control groups (oe-LIFR-AS1: HT-29 or T84 cells transfected with LIFR-AS1 expression plasmid; NC: HT-29 or T84 cells transfected with the empty vector)

Back to article page

Clinical Epigenetics

ISSN: 1868-7083

Contact us