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Fig. 4 | Clinical Epigenetics

Fig. 4

From: DNA methylation signatures on vascular differentiation genes are aberrant in vessels of human cerebral arteriovenous malformation nidus

Fig. 4

Promoter DNA methylation analysis by bisulfite conversion and sequencing. a The selected promoter region of FAAH gene, and the CpGs are marked in red color. The bottom image is the result from the BISMA analysis of clones amplified from control and AVM nidus samples after bilsulfite conversion. The column number represents the CpG and the clones represent the amplicons. b The CpGs in AGGF1 gene promoter are marked in red color and the results of the clones amplified from control and AVM tissues from BISMA analysis. The blue color box represent the unmethylated CpG and red color box represent the methylated CpG. Percentage of methylated CpGs are provide at the bottom of the image

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