Skip to main content
Fig. 3 | Clinical Epigenetics

Fig. 3

From: DNA methylation signatures on vascular differentiation genes are aberrant in vessels of human cerebral arteriovenous malformation nidus

Fig. 3

Promoter DNA methylation analysis by bisulfite conversion and sequencing. a The selected promoter region of ZNF24 gene for methylation analysis, and the CpGs are marked in red color. The bottom image represents the output from the BISMA analysis (Rhode et al. 2009) of clones prepared from control and AVM nidus samples. The column number represents the CpG and the clones represents the amplicons. b The CpGs in ANKSRD65 gene promoter are marked in red color and the bottom results is the output from BISMA analysis of the clones. The clones amplified from cerebral AVM has the significantly higher number of methylated CpG than control tissue. The blue color box represent the unmethylated CpG and red color box represent the methylated CpG. Percentage of methylated CpGs are provide at the bottom of the image

Back to article page

Clinical Epigenetics

ISSN: 1868-7083

Contact us