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Fig. 2 | Clinical Epigenetics

Fig. 2

From: DNA methylation signatures on vascular differentiation genes are aberrant in vessels of human cerebral arteriovenous malformation nidus

Fig. 2

Infinium bead ChIP array for DNA methylation analysis. a The heatmap represent the the hypermethylated CpGs located in the promoter regions of genes. We have two control tissues and two AVM tissues and top 100 hypermethylated genes were used to generate the heatmap. The red color indicates the hypermethylation, and blue color indicates the DNA hypomethylation. There were significant number of CpGs were shown hypermethylation. b The heatmap represents the hypomethylated CpGs of the cerebral AVM nidus. There were not much significant DNA hypomethylation was observed among the duplicate’s samples of AVM. c The list of hypermethylated CpGs of AVM nidus and its nearest genes, the list is extracted from (a)

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Clinical Epigenetics

ISSN: 1868-7083

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