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Table 4 CpGs with p values < 1.0 * 10–6 from epigenome-wide association study of a mixture of phthalates and bisphenols in maternal urine during first, second and third trimester and DNA methylation in cord blood among boys

From: Fetal exposure to phthalates and bisphenols and DNA methylation at birth: the Generation R Study

 

CpG

Chr

Position

Gene

Effect

SE

p value

Flag#

Second trimester

cg03764767

1

2338210

PEX10

− 1.85 * 10–2

3.33 * 10–3

1.36 * 10–7

1

Third trimester

cg23462052

20

2452871

SNRPB

1.27 * 10–2

2.36 * 10–3

2.65 * 10–7

1

  1. There were no CpGs presented for first trimester, as none reached our uncorrected p value cutoff of < 1.0 * 10–6. There were no associations that reached significance (p value < 0.05) after further FDR-adjustment of the p value for multiple testing including the three trimesters
  2. #We have indicated probes that map to DNA containing a single nucleotide polymorphism (SNP), repetitive sequence elements or DNA harboring an insertion or deletion with a ‘1’ in this column