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Fig. 5 | Clinical Epigenetics

Fig. 5

From: The absence of AhR in CD4+ T cells in patients with acute graft-versus-host disease may be related to insufficient CTCF expression

Fig. 5

DNA hypermethylation and histone H3K9/14 hypoacetylation of the AhR promoter in aGVHD CD4+ T cells. A DNA methylation levels of the AhR promoter in CD4+ T cells from patients with aGVHD (n = 10) and the non-aGVHD group (n = 10). B, C ChIP-qPCR analysis of histone H3K9 (B) and H3K14 C acetylation levels in the AhR promoter in CD4+ T cells of patients with aGVHD (n = 10) and the non-aGVHD group (n = 10). Results are relative to input DNA prepared from untreated chromatin. D, F Correlation analysis of DNA methylation (D), H3K9 (E)/H3K14 F acetylation and AhR mRNA levels. (*P < 0.05, **P < 0.01)

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Clinical Epigenetics

ISSN: 1868-7083

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