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Fig. 2 | Clinical Epigenetics

Fig. 2

From: The absence of AhR in CD4+ T cells in patients with acute graft-versus-host disease may be related to insufficient CTCF expression

Fig. 2

Restoring AhR expression in aGVHD CD4+ T cells increases Treg cell amounts and reduces Th17 cell levels. A Representative Western blot showing AhR protein levels in aGVHD CD4+ T cells transfected with the AhR expression (pCMV6-AhR) or control (pCMV6) plasmid. B The percentages of Treg and Th17 cells in the AhR expression plus ITE treatment and transfection control plus vehicle control groups were detected by flow cytometry. C Statistical analysis of flow cytometry data. D, E Expression of genes associated with Tregs (D) and Th17 cells E assessed by real-time PCR. Data represent the means of three independent experiments (*P < 0.05, **P < 0.01)

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Clinical Epigenetics

ISSN: 1868-7083

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