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Table 1 Common differentially expressed proteins in MOLM-13 compared to the untreated control after exposure to either 0.5 µM AzadC or 1.0 µM AzaC or 2.5 µM AzaC for 72 h

From: Comprehensive comparison between azacytidine and decitabine treatment in an acute myeloid leukemia cell line

Protein

Uniprot ID

log2 FC

1.0 µM AzaC

2.5 µM AzaC

0.5 µM AzadC

CNBP (CCHC-type zinc finger nucleic acid binding protein)

P62633

− 6.02

− 4.59

− 3.45

ATP5D (ATP synthase subunit delta, mitochondrial)

P30049

− 4.64

− 5.14

− 3.62

RPL35 (60S ribosomal protein L35)

P42766

− 4.60

− 5.14

− 3.62

RPL32 (60S ribosomal protein L32)

P62910

− 3.68

− 3.98

− 3.57

PSMB6 (Proteasome subunit beta type-6)

P28072

− 3.38

− 3.69

− 3.32

WTAP (Pre-mRNA-splicing regulator WTAP)

Q15007

− 2.39

− 2.76

− 2.15

ATG3 (Ubiquitin-like-conjugating enzyme ATG3)

Q9NT62

− 2.23

− 1.93

− 1.61

DNMT1 (DNA (cytosine-5) methyltransferase 1)

P26358

− 2.19

− 1.87

− 1.49

NOL7 (Nuclear protein 7)

Q9UMY1

− 2.12

− 2.33

− 2.86

PLAUR (Urokinase plasminogen activator surface receptor)

Q03405

− 1.97

− 2.18

− 2.33

RRP1B (Ribosomal RNA processing protein 1 homolog B)

Q14684

− 1.94

− 2.00

− 2.66

IRF8 (Interferon regulatory factor 8)

Q02556

− 1.68

− 1.13

− 1.43

MRPL13 (39S ribosomal protein L13, mitochondrial)

Q9BYD1

− 1.53

− 1.24

− 1.37

PTER (Phosphotriesterase-related protein)

Q96BW5

− 1.40

− 2.00

− 2.35

HBS1L (HBS1-like protein)

Q9Y450

− 1.27

− 1.51

− 1.14

PRRC2C (Protein PRRC2C)

Q9Y520

− 1.22

− 0.75

− 1.22

GPT2 (Alanine aminotransferase 2)

Q8TD30

− 1.12

− 0.99

− 1.09

TNKS1BP1 (182 kDa tankyrase-1-binding protein)

Q9C0C2

− 0.98

− 1.54

− 1.59

SATB1 (DNA-binding protein SATB1)

Q01826

− 0.72

− 0.61

− 0.92

DLD (Dihydrolipoyl dehydrogenase, mitochondrial)

P09622

− 0.65

− 0.63

− 1.48

CYB5R3 (NADH cytochrome b5 reductase 3)

P00387

0.62

0.67

0.70

NUBP2 (Cytosolic Fe-S cluster assembly factor NUBP2)

Q9Y5Y2

1.10

1.33

1.66

PPP6R2 (Serine/threonine-protein phosphatase 6 regulatory subunit 2)

O75170

1.13

1.29

1.31

RSF1 (Remodeling and spacing factor 1)

Q96T23

1.24

1.04

0.91

TKTL1 (Transketolase-like protein 1)

PS1854

1.89

3.00

1.50

PEA15 (Astrocytic phosphoprotein PEA-15)

Q15121

1.94

2.01

0.94

TEX10 (Testis-expressed protein 10)

Q9NXF1

2.01

2.27

1.84

ICT1 (Peptidyl-tRNA hydrolase ICT1, mitochondrial)

Q14197

2.09

1.72

1.38

CFD (Complement factor D)

P00746

2.22

2.21

3.05

MPO (Myeloperoxidase)

P11247

2.68

2.62

2.86

GATD3 (Gln amidotransferase-like class 1 domain-cont. protein 3)

P0DPI2

3.38

3.70

4.58

  1. For all proteins listed, the log(p value) was > 1.30 in all three data sets