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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Genomic targets and selective inhibition of DNA methyltransferase isoforms

Fig. 4

Analysis of repetitive elements. A DNA methylation at loci mapping to LINES, SINES, long terminal repeats (LTR), satellite DNA, regions of low complexity, and simple repeats. B Gains of methylation of Δβ > 0.2 (light purple), Δβ > 0.3 (medium purple) and Δβ > 0.4 (dark purple) at loci mapping to repetitive elements in response to DNMT isoform overexpression. C Correlation between changes in DNA methylation (Δβ) at Alu subfamilies by their time since integration within the genome (million years ago, MYA)

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