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Table 2 Influences of the number of probes, mean variability and methylation QTL status on DNAm-based predictions

From: Identification of influential probe types in epigenetic predictions of human traits: implications for microarray design

Probe classification

Starting nprobe

115,746

50,000

20,000

10,000

Probes without known mQTL

115,746

6.7%

6.6%

5.6%

5.0%

Probes with known mQTL

144,150

9.0%

8.1%

6.2%

4.8%

Hypo- and hypermethylated probes

133,758

4.2%

4.0%

3.3%

2.8%

EWAS Catalog probes

38,853

–

–

8.7%

8.0%

  1. Metric shown is the average % of variance captured in seventeen biochemical and complex traits by DNAm-based predictors. mQTL, methylation QTL