Table 1 Influences of the number of probes, mean variability and methylation QTL status on variance component estimates
Probe classification | Starting nprobe | 115,746 | 50,000 | 20,000 | 10,000 |
|---|---|---|---|---|---|
Probes without reported mQTL | 115,746 | 47.9% | 40.6% | 30.4% | 21.9% |
Probes with reported mQTL | 144,150 | 48.0% | 38.7% | 26.1% | 16.5% |
Hypo- and hypermethylated probes | 133,758 | 38.7% | 37.9% | 27.7% | 18.4% |
EWAS Catalog probes | 38,853 | – | – | 32.9% | 24.4% |