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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Low reliability of DNA methylation across Illumina Infinium platforms in cord blood: implications for replication studies and meta-analyses of prenatal exposures

Fig. 1

Overview of the ICC distribution computed from raw data and from data pre-processed using the default settings of five common EWAS analysis pipelines. Additionally, we included one common analysis pipeline (“RnBeads (customised)”, including the normalisation methods ENmix.oob and BMIQ). All pipelines examined also exhibited ICCs lower than –2, but these were removed from the illustration for visualisation purposes. The default settings of each analysis pipeline are detailed in Additional file 1: Table S1

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Clinical Epigenetics

ISSN: 1868-7083

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