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Fig. 9 | Clinical Epigenetics

Fig. 9

From: Genome-wide promoter methylation profiling in a cellular model of melanoma progression reveals markers of malignancy and metastasis that predict melanoma survival

Fig. 9

Risk scores for melanoma survival calculated from CpG methylation malignancy and metastasis-related panels accurately separate samples into low and high-risk groups. Kaplan–Meier plots show survival of high and low risk patients according to a (A) Malignancy Risk Score (HR = 3.29 [2.48–4.37]), and (B) Metastasis Risk Score (HR = 1.84 [1.56–2.16]), both obtained from the respective signatures of CpG methylation status, containing, respectively, 33 and 31 CpGs

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