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Fig. 6 | Clinical Epigenetics

Fig. 6

From: Genome-wide promoter methylation profiling in a cellular model of melanoma progression reveals markers of malignancy and metastasis that predict melanoma survival

Fig. 6

Distribution of hyper- and hypomethylated CpGs correlated with melanoma patients’ outcomes according to their genome location and number of associated genes. A The number of hyper- and hypomethylated CpGs correlated with overall survival is shown according to their location in islands, shores, shelves and open sea regions, for malignancy and metastasis signatures. B The distribution of hyper- and hypomethylated CpGs along genomic regions is shown according to their correlation with a good or poor prognosis for malignancy and metastasis signatures. C. The number of genes from both signatures containing at least two CpGs correlating with melanoma patient outcome is shown

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