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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Genome-wide promoter methylation profiling in a cellular model of melanoma progression reveals markers of malignancy and metastasis that predict melanoma survival

Fig. 2

The pattern of differentially methylated CpGs distributed across genomic features and transcription features. A Cell lines used in this study that represent different stages of melanoma progression. B Number of hypermethylated (red) and hypomethylated (blue) individual cytosines in CpG context per pairwise comparison among all the four cell lines. DMCs according to their location in islands, shores, and other regions are represented in C, D, and E, respectively. Annotation of all hypomethylated (F) and hypermethylated (G) CpGs by region related to transcription: promoter (salmon), exon (blue), intron (green) and intergenic (purple) for each pairwise comparison

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Clinical Epigenetics

ISSN: 1868-7083

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