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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Differentially methylated CpGs in response to growth hormone administration in children with idiopathic short stature

Fig. 2

The distribution of response-dependent differentially methylated CpGs. A The QQ-plot of p values from the analysis of the CpGs respond to the GH treatment. B Manhattan plot of p values from the response analysis. C The heatmap of response DMCs at p value < 1e−3 whose methylation profiles were measured for all individuals. Different phenotype features (including different sequencing platforms, sex, puberty, age onset, treatment duration, changes of IGF1 concentration and GH dose) are illustrated in the top plots. D–G Scatter plot for the examples of top response DMCs. The sex and treatment duration were indicated with different colors and different sizes of the dots

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Clinical Epigenetics

ISSN: 1868-7083

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