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Table 4 Molecular analyses of BWS alterations in babies born from PMD-complicated pregnancies

From: Aberrant hypomethylation at imprinted differentially methylated regions is involved in biparental placental mesenchymal dysplasia

PMD status

Number of babies

Number of babies with BWSp score ≥ 4

Molecular testing

ABM-PMD

12

2

ABM (paternal uniparental diploidy), no alteration

Biparental-PMD

9

2

ICR2-LOM, patUPD

Biparental-normal*

1

0

 
  1. ICR2-LOM loss of methylation at imprinting control region 2, patUPD segmental paternal uniparental disomy of chromosome 11p
  2. *PMD-028, in which the cystic region shrank during pregnancy
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Clinical Epigenetics

ISSN: 1868-7083

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