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Fig. 4 | Clinical Epigenetics

Fig. 4

From: LINC00114 stimulates growth and glycolysis of esophageal cancer cells by recruiting EZH2 to enhance H3K27me3 of DLC1

Fig. 4

Knocking down DLC1 enhances growth and glycolysis of EC cells. A, B RT-qPCR detected DLC1 expression in tissue samples (EC tissues and non-tumoral tissues) and cells (HEEC and EC cells); C, D RT-qPCR and Western blot detected the transfection efficiency of si-DLC1 in Eca109 and TE1 cells; E CCK-8 detected proliferation of EC cells after DLC1 interference; F colorimetry detected glucose consumption in EC cells after DLC1 interference; G lactic acid determination kit II detected lactic acid production in EC cells after DLC1 interference; H ATP colorimetric determination kit detected ATP level in EC cells after DLC1 interference; data were shown as mean ± standard deviation. N = 3; & P < 0.05 versus HEEC. *P < 0.05 versus the si-NC group

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Clinical Epigenetics

ISSN: 1868-7083

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