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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Physical activity specifically evokes release of cell-free DNA from granulocytes thereby affecting liquid biopsy

Fig. 1

Concentration and origin of cfDNA in healthy persons during exercise and patients with hematological malignancies. A cfDNA concentration in blood plasma. B Heatmap of the percentage of methylation of the given CpGs in the reference matrix. C, D Deconvolution results indicating the origin of cfDNA samples before and after exercise in healthy subjects. E Spearman correlation matrix between cfDNA, blood counts, and deconvolution results. F Differences in cell type specific cfDNA proportions between healthy and diseased persons at rest. In all analysis P < .05 was considered significant. *P < .05, **P < .01, ***P < .001, ****P < .0001, ns: not significant

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Clinical Epigenetics

ISSN: 1868-7083

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